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Biomed Microdevices ; 20(1): 4, 2017 Nov 23.
Artigo em Inglês | MEDLINE | ID: mdl-29170867

RESUMO

Three-dimensional (3D) printing is an emerging technique in the field of biomedical engineering and electronics. This paper presents a novel biofabrication method of implantable carbon electrodes with several advantages including fast prototyping, patient-specific and miniaturization without expensive cleanroom. The method combines stereolithography in additive manufacturing and chemical modification processes to fabricate electrically conductive carbon electrodes. The stereolithography allows the structures to be 3D printed with very fine resolution and desired shapes. The resin is then chemically modified to carbon using pyrolysis to enhance electrochemical performance. The electrochemical characteristics of 3D printing carbon electrodes are assessed by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The specific capacitance of 3D printing carbon electrodes is much higher than the same sized platinum (Pt) electrode. In-vivo electromyography (EMG) recording, 3D printing carbon electrodes exhibit much higher signal-to-noise ratio (40.63 ± 7.73) than Pt electrodes (14.26 ± 6.83). The proposed biofabrication method is envisioned to enable 3D printing in many emerging applications in biomedical engineering and electronics.


Assuntos
Eletrodos , Impressão Tridimensional , Animais , Carbono/química , Espectroscopia Dielétrica , Condutividade Elétrica , Estimulação Elétrica/instrumentação , Eletrodos Implantados , Eletromiografia/instrumentação , Desenho de Equipamento , Masculino , Ratos Sprague-Dawley , Razão Sinal-Ruído , Termogravimetria
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